Tetracycline antibiotics. Doxycycline reversibly binds to receptors on the 30S subunit of bacterial ribosomes, interfering with the formation of ribosomal complexes between tRNA and mRNA, preventing peptide chain elongation and inhibiting protein synthesis, thereby rapidly inhibiting bacterial growth and reproduction. Doxycycline has inhibitory effects on both Gram positive and negative bacteria. Bacteria have cross resistance to doxycycline and oxytetracycline.
Internal absorption is rapid, less affected by food, high bioavailability, strong tissue permeability, widely distributed, and effective blood drug concentration is maintained for a long time. The protein binding rate in pigs is 93%.

1. When treating porcine eperythrozoon, I prefer to use doxycycline sulfonamide drugs together for intramuscular injection. The effect is very significant. Due to the fact that eperythrozoon is a pig disease that enjoys playing around. Under normal circumstances, it can cause fever in pigs and urine to turn yellow. Skin turns red. So when choosing medication, it is also necessary to choose Shuanghuanglian, Lincomycin, and Soda powder for comprehensive treatment. Shuanghuanglian can clear heat, detoxify, and reduce fever. Lincomycin, anti-inflammatory and analgesic, soda powder to neutralize stomach acid, alkalize urine.
2. During pig castration, if many purple dots are found on the belly of the piglet, they are densely packed. If you castrate a pig, its immune function decreases under stress. It is easy to have Eperythrozoon. At this time, during the same period of castration, it is necessary to use doxycycline seasoning for 5 days. It can effectively prevent the outbreak of Eperythrozoosis.
3. Lactating piglets often have feces that are yellow with white and white with gray after seven days. When you use various anti dysentery antibiotics such as enrofloxacin and amphotericin for treatment without success, if you choose doxycycline and sulfonamide drugs for intramuscular injection, the effect is often unexpected. This is because the piglet may have been infected with Eperythrozoon or coccidia.
4. Our fat pigs often experience fever rebound during the dog days, and it keeps going back and forth. If you use various antibiotics and sulfonamide drugs to treat without success, if you switch to doxycycline and add Shuanghuanglian for intramuscular injection, the rebound will no longer occur.