Sulfate colistin belongs to the peptide class of fungicides. It has strong antibacterial effects on Gram negative bacteria such as Escherichia coli, Salmonella, Pasteurella, Shigella, Brucella, Vibrio, and Pseudomonas aeruginosa, with strong bactericidal effects on Pseudomonas aeruginosa and Vibrio. The antibacterial mechanism of it lies in its binding with the free phosphate groups of lipoproteins in the cell membrane of sensitive bacteria, which increases the permeability of the cell membrane. Purines and pyrimidines in the cell escape from the cytoplasm, leading to the gradual death of the bacteria. Long term addition to feed has a significant growth promoting effect.

1. The treatment of piglet yellow and white dysentery, edema disease, swine dysentery, typhoid fever, and paratyphoid fever caused by Escherichia coli and Salmonella infections is significantly effective.
2. The therapeutic effect is definite for persistent diarrhea, unexplained diarrhea, piglet weaning, and watery diarrhea caused by changing materials stress.
3. Treat enteritis, dysentery, etc. caused by Shigella, Pseudomonas aeruginosa, Leptospira suis, Treponema pallidum, etc.
4. Treat poultry diarrhea, pneumocystis, pericarditis, perihepatitis, peritonitis, salpingitis, hemorrhagic enteritis, acute sepsis caused by highly pathogenic Escherichia coli, and complications caused by Escherichia coli.
5. Treatment for ulcerative or necrotic enteritis, chicken dysentery, avian cholera, typhoid fever, paratyphoid fever, and severe bacterial infections in poultry, causing mental distress, intestinal mucosal congestion, bleeding, gray white, yellow white or green feces or watery feces, loose feces sticking to the anus, loose feathers, poor blood, red or even black brown coal tar like dysentery, etc.